caution larry

Hi, I’m Kim! This site provides a little insight to my journey of being diagnosised with Remitting Relapsing Multiple Sclerosis on October 26th 2004. I review books and documentaries, post MS-related news, and share my photos.

Subscribe (RSS)

no larry

My bloglines



November 2004
December 2004
January 2005
February 2005
March 2005
April 2005
May 2005
June 2005
July 2005
August 2005
September 2005
October 2005
November 2005
December 2005
January 2006
February 2006
March 2006
April 2006
May 2006
June 2006
July 2006
August 2006
September 2006
October 2006
November 2006
December 2006
January 2007
February 2007
March 2007
April 2007
May 2007
June 2007
July 2007
August 2007
September 2007
October 2007
November 2007
December 2007
January 2008
February 2008
March 2008
April 2008
May 2008
June 2008
July 2008
August 2008
September 2008
October 2008
November 2008
December 2008
January 2009
February 2009
March 2009
April 2009
May 2009
June 2009
July 2009
August 2009
September 2009
October 2009
November 2009
December 2009
January 2010
February 2010
March 2010
May 2010
June 2010
July 2010
September 2010
November 2011


Wednesday, February 25, 2009
The nephew continues to get cuter :)

3 1/2 month old now!

I just signed up today for the MS walk as team captain for Team Mandatory Rest Period! Anyone here in the lower mainland want to join my team? I'll be walking the Tri-cities walk on April 26th.

Thursday, February 19, 2009
Less Claustrophic MRI Machines on the Way?

"Currently, for the MRI to work, radio frequency coils which deliver the magnetic waves must be nearly flush against a patient's skin hence the confining scanner tubes.

But David Brunner, a physicist at the University of Zurich, and colleagues have seen early success in replacing the coils with an antenna up to 9.8 feet (3 meters) away from a patient.

The antenna transmits and receives the radio frequency waves, which are focused by a special conductive lining inside the MRI scanning tube.

"Very Promising"

The extra room "will usually be on the order of 15-20 centimeters [6-8 inches] in diameter, which really is a lot in terms of patient comfort," said study co-author Klaas Pruessmann, also of the University of Zurich.

What's more, the "traveling waves" transmitted by the antenna offer more uniform coverage of large body parts and greater detail, said study co-author Klaas Pruessmann, also of the University of Zurich.

The technology "is currently being explored in centers around the world, including many in the U.S., and early pre-clinical applications look very promising," Pruessmann said.

Peter Bornert, principal scientist at Philips Research Europe in Hamburg, Germany, called the new technique "very promising from a scientific point of view" pointed out that several previous successful attempts to improve MRI in the lab have not yet made it to market.

Tuesday, February 17, 2009
A good strong...


Echo and Flick, brother and sister.

Laquinimod, was granted "fast track" designation by the FDA

An oral med is moving forward with getting reviewed by the FDA a little bit faster than usual. Yay! Okay, I say yay for Liquinimod but really I would have liked to see my oral drug (Fingolimod) in this press release instead ;)

"Teva's oral treatment for multiple sclerosis, Laquinimod, was granted "fast track" designation by the US Food and Drug Administration (FDA). Fast Track designation can potentially facilitate development and expedite the review process. According to Teva, this may allow the drug to enter the market as soon as late 2011."

Sunday, February 15, 2009
Don't mind me, folks - just fixing Kim's RSS feed. The link (which will be updated) is

Nothing to see here. Move along. Enjoy the rest of your weekend.

Thursday, February 12, 2009
Electrical shocks while driving
This is a new one for me. I was driving home from work yesterday and my left foot starting jumping. It felt like someone plugged in my big toe to an electrical socket and kept jolting me unexpectedly. Thank god I don't drive a standard! It was unnerving and continued for about a half hour. Not constant but here and there for maybe 2 seconds each time. Can you say annoying??!!

Tuesday, February 10, 2009
Vitamin D Deficiency May Increase MS Risk
Well, well, well... finally! A link to MS with the infamous Vitamin D we've all been hearing about for many years. And I find it quite cool to also see an environmental trigger identified to tell me why I have MS! Go research go!

"The findings could explain why MS, an autoimmune condition in which the body mistakenly attacks brain tissue and nerves, is relatively rare in countries near the sunny equator. MS is much more common in the darker and gloomier northern latitudes (and far southern latitudes).

Other studies have suggested that people with MS were more likely to have been born in the spring (with the bulk of pregnancy during the dark winter months) than in the fall. Sunlight is the main source of vitamin D, although it’s also found in salmon, mackerel, tuna fish, and as an additive to milk and other products.

“It’s a phenomena found over and over again, says Moses Rodriguez, MD, a professor of neurology at the Mayo Clinic in Minnesota, who was not involved in the new research. “This study provides some link that vitamin D may be one of the environmental factors that predisposes people to MS.

No one really knows the exact cause of MS, but researchers suspect it’s a combination of genes and environmental factors. About 2.5 million people worldwide have MS.

In the study, researchers from the University of Oxford and the University of British Columbia looked at a gene variant known as DRB1*1501, which is associated with MS. About 1 in 100 people who inherit two copies of the gene (one from each parent) develop MS, compared to 1 in 300 who have only one copy and 1 in 1,000 of those in the general population.

The researchers found that proteins activated by vitamin D bind to a DNA sequence next to the DRB1*1501 variant, which switches the gene on. If too little vitamin D is present, the gene may not function properly, which may cause a susceptibility to MS.

"We were surprised to find the [vitamin] D connection," says study coauthor George Ebers, action research professor of clinical neurology at the University of Oxford. “We suspect women who are planning to have children may benefit from taking D in regions where they are likely to be deficient.

There is no proof that vitamin D will prevent, treat, or cure the disease. However, the researchers suspect that a lack of vitamin D during early life may prevent the thymus, an immune system gland that sits on the top of the heart, from deleting harmful white blood cells.

These cells, known as T cells, may go on to attack the central nervous system and damage myelin, the insulation that protects nerves. In MS, this abnormal immune response affects nerve impulses to and from the brain. Symptoms of MS include numbness in the limbs, pain, coordination problems, vertigo, and vision impairment, depending on the nerves that are affected.

Sleep clinic appointment update

Well, I finally had my sleep clinic appointment. What a great experience. Without medications, I am going to be trying to modify a few things that make a whole lot of sense to help me get a better sleep. The big one that never occurred to me is to regulate my "waking up" time. So over the next couple of weeks, I need to pick what time I will wake up at 7 days a week. Naturally, it seems that my body does always wake up at 6:30ish, so that may be what I try. Bye, bye sleep in mornings. This should be an interesting change. I guess your body works better when it knows when it always has to wake up. We'll see!

Reset button called Stem Cell Transplant

A small trial is showing some good results on what stem cells can do in MS.

"Stem cell transplantation seems to stop and, in some cases, undo neurological damage in people with multiple sclerosis, a small study shows.

The trial involved just 21 patients, but a larger, randomized trial is under way in the United States, Canada and Brazil.

"This is the first trial for any phase of MS, whether early or later, of any therapy anywhere that has shown reversal of neurological disability," said study author Dr. Richard K. Burt, chief of the division of immunotherapy at the Northwestern University Feinberg School of Medicine in Chicago.

The technique used in this study, autologous non-myeloablative hemopoietic stem cell transplantation, "resets" the immune system and is already used for secondary-progressive MS.

"This has primarily been used over the last 10 to 15 years in progressive MS patients, people who are doing terribly, and we have nothing to offer them," O'Looney explained. "There have been some fatalities associated with this aggressive protocol."

And success was limited.

But, for the new study, researchers tweaked the technique and moved it to relapse-remitting patients who were younger than in previous studies.

"This is a safer approach, and we do it earlier in the disease because people have less disability so it's safer again," Burt said.